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KMID : 0356919920250030596
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Korean Journal of Anesthesiology
1992 Volume.25 No. 3 p.596 ~ p.601
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The Effects of Depolarizing and Nondepolarizing Muscle Relaxants on Postoperative Sore Throat, Hoarseness, and Myalgia
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우영철
김형미/임상호/박영철/이미경/김난숙/최영석
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Abstract
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The relationship between different muscle relaxants(vecuronium, pancuronium, succinylcholine) and postoperative sore throat, hoarseness, and myalgia was evaluated in 46 adult ASA class I women undergoing general anesthesia with endotracheal
intubation.
All patients were anesthetized with thiopental-N2O-O2 and enflurane. The patients were divided into 3 groups. Patients in group 1(n=15) were given vecuronium, group 2(n=16) pancuronium, and group 3(n=15) succinylcholine. Patient interviews were
conducted at 6~10 hours(h) and 24~30 hpostoperatively. Evaluation for severity of sore throat, hoarseness and myalgia was accomplished by scoring according to specific criteria. In groups 1, 2, and 3, 6~10 h postoperatively, the incidence of sore
throat
was 40% , 50% , and 33%; hoarseness was 40%, 31% and 27%;myalgia was 13%, 6% and 20% respectively. IN groups 1,2 and 3, 24~30 h postoperatively, the incidence of sore throat was 7%, 25%, and 53%; hoarseness was 13%, 31%, and 33%; myalgia was 13%,
19%,
and 33% respectively.
The use of succinylcholine(Sch) resulted in higher incidence of postoperative sore throat at 24~30 h compared with 6~10h(p<0.05). These results suggest that administration of SCh may contribute to the occurrence of postoperative sore throat.
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